Oneness Biotech Co., Ltd. receives a Canadian patent titled “TOPICAL FORMULATION FOR PROMOTING WOUND HEALING” on Fespixon cream (Research code: ON101).

Statement
No	1	Date of announcement	2025/11/12	Time of announcement	16:54:15
Subject	Oneness Biotech Co., Ltd. receives a Canadian patent titled “TOPICAL FORMULATION FOR PROMOTING WOUND HEALING” on Fespixon cream (Research code: ON101).
To which item it meets	Subparagraph 53			Date of events	2025/11/12
Date of occurrence of the event：2025/11/12 Company name: ONENESS BIOTECH CO., LTD Relationship to the Company (please enter ”head office” or ”subsidiaries”):head office Reciprocal shareholding ratios: NA Cause of occurrence: The Company has been informed by the patent agency that a Canadian patent titled ”TOPICAL FORMULATION FOR PROMOTING WOUND HEALING” has been granted on the new drug Fespixon cream (Research code: ON101) under the patent number CA 3030774. Countermeasures:None Any other matters that need to be specified(the information disclosure also meets the requirements of Article 7, subparagraph 9 of the Securities and Exchange Act Enforcement Rules, which brings forth a significant impact on shareholders rights or the price of the securities on public companies.): The new drug, Fespixon cream has been granted many international patents. The development of new drugs is lengthy so many new drugs are faced with expiring patent protection shortly after their market approval, which results in loss of market exclusivity. The Company has filed a new patent for the topical formulation of Fespixon cream with innovative and efficacious scientific data and has been granted such patent in many countries around the world. During the term of the granted patent, Fespixon cream will be protected against any generic competition.